gmp-001

GMP KnowledgeGeneral Gmpeasy

Question

According to 21 CFR 211.192, what is required when any unexplained discrepancy or failure of a batch to meet specifications is found?

Choices

A. The batch should be immediately destroyed
B. A thorough investigation should be made, extending to other batches that may have been associated with the specific failure or discrepancy
C. Only the affected batch needs to be quarantined; no investigation is needed
D. The discrepancy can be noted in the batch record without further action

Cross-Model Comparison

Model	Score	Latency	Tokens In	Tokens Out
Qwen3.8-Flash	N/A	N/A	-	-
GLM-5.3	N/A	N/A	-	-
MiniMax M3	N/A	N/A	-	-
Hy4 Preview	N/A	N/A	-	-
Muse Glimmer 30B	N/A	N/A	-	-
Qwen3.8 Max (2.4T-A95B)	N/A	N/A	-	-
Claude Sonnet 4.6	100.0%	8.1s	115	322
Llama 4 Scout	100.0%	5.1s	108	401
Claude Opus 4.6	100.0%	9.2s	115	332
Llama 4 Maverick	100.0%	6.4s	109	406
Llama 3.3 70B Instruct	100.0%	1.9s	110	178
Mistral Small 2603	100.0%	1.7s	119	279
Qwen3.5-397B-A17B	100.0%	12.7s	115	844
DeepSeek-R1	100.0%	12.1s	107	406
DeepSeek-R1-Distill-Qwen-32B	100.0%	52.1s	107	615
Mistral Large 3 675B	100.0%	3.4s	107	199
Gemini 3 Flash	100.0%	2.0s	102	138
DeepSeek V4 Pro	100.0%	6.6s	101	354
Gemini 3.1 Pro	100.0%	6.5s	102	607
Gemini 3.1 Flash-Lite	100.0%	1.4s	102	143
Qwen3.6 27B	100.0%	19.8s	115	897
DeepSeek V4 Flash	100.0%	3.2s	161	156
Qwen3.6 35B A3B	100.0%	5.1s	115	1,066
DeepSeek-V3.2	100.0%	4.0s	101	107
DeepSeek V4 Flash	100.0%	4.2s	101	405
Gemma 4 26B A4B IT	100.0%	2.9s	115	160
Gemma 4 31B IT	100.0%	7.5s	115	139
Llama 4 Maverick	100.0%	11.0s	166	330
Claude Opus 4.8	100.0%	5.4s	150	327
GLM-5.2	100.0%	11.7s	111	358
Qwen3.8 27B	100.0%	8.2s	219	277
Llama 4 Scout	100.0%	8.0s	166	225
Llama 3.3 70B Instruct	100.0%	47.7s	169	357
Mistral Small 2603	100.0%	2.8s	182	341
Qwen3.5-35B-A3B	100.0%	8.8s	177	1,017
Mistral Large 3 675B	100.0%	2.2s	170	148
Qwen3.6 27B	100.0%	30.5s	177	1,112
Qwen3.6 35B A3B	100.0%	6.9s	177	1,409
Hy4 Preview	100.0%	8.8s	178	673
Qwen3.5-397B-A17B	100.0%	6.9s	177	568
DeepSeek V4 Pro	100.0%	6.9s	161	56
DeepSeek-V3.2	100.0%	6.2s	167	133
Claude Sonnet 5	100.0%	1.3s	238	9
Gemma 4 26B A4B IT	100.0%	2.8s	177	204
DeepSeek-R1	100.0%	59.8s	160	927
Gemma 4 26B A4B IT	100.0%	7.8s	177	212
Gemma 4 31B IT	100.0%	12.5s	177	184
MiniMax M2.7	100.0%	5.6s	198	419
GLM-5.2	100.0%	17.5s	171	549
Kimi K3	100.0%	11.1s	244	401
Muse Glimmer 30B	100.0%	6.1s	213	389
GLM-5.3-Flash	100.0%	6.7s	171	255
GPT-5.6 Luna	100.0%	1.7s	162	88
GPT-5.4 mini	100.0%	736ms	104	30
MiniMax M2.7	100.0%	2.5s	139	310
GPT-5.4 nano	100.0%	1.4s	104	69
Claude Haiku 4.5	100.0%	2.4s	115	273
DeepSeek-V3.2	100.0%	24.2s	101	109
GPT-5.4	100.0%	1.6s	104	67
Qwen3.8 Max (2.4T-A95B)	100.0%	2.1s	219	181
Qwen3.8-Flash	100.0%	1.7s	228	138
MiniMax M3	100.0%	1.8s	333	324
GLM-5.3	100.0%	1.8s	172	147
Claude Opus 5	100.0%	7.6s	238	449
Claude Haiku 4.5	100.0%	2.5s	179	232
GPT-5.6 Sol	100.0%	2.1s	162	47
GPT-5.6 Terra	100.0%	1.8s	162	68
Qwen3.5-35B-A3B	0.0%	6.0s	115	1,039

gmp-001

Cross-Model Comparison

Tags